Searchable abstracts of presentations at key conferences in obesity

ob0001p47 | (1) | UKCO2019

DNA methylation biomarkers of early life rapid weight gain: Findings from the Newcastle Thousand Families Study and the Avon Longitudinal Study of Parents and Children

Robinson Natassia , Brown Heather , Pearce Mark , Byun Hyang-Min , McKay Jill

Background: The associations between early life factors and obesity in later life may be mediated through epigenetic mechanisms such as DNA methylation. Infancy rapid weight gain (RWG) is one early life factor that has been consistently associated with increased risk of obesity in childhood. We investigated if early life rapid weight gain (+0.67SD change in weight for age z-score from birth to 1 year), was associated with variation in DNA methylation in childhood and adulthood...